The study we first calculated the level of spontaneous mutagenesis population of Yemen Republic residents, which amounted to 1,12 ± 0,09 per 100 cells. The main type of aberrations in this were single fragments (0,69 ± 0,10%), which occurred twice as often paired (0,35 ± 0,07%). Chromosomal exchanges and chromatid exchanges occurred at a frequency 0,02 ± 0,02% and 0,08 ± 0,04% at 1.96% of the population. In the analyzed material was observed dysenteric chromosomes interchromatid, interchromosomal exchanges, which may indicate the absence of the effects of radiation and chemicals above background.
Inhaltsverzeichnis (Table of Contents)
- INTRODUCTION
- MATERIALS AND METHODS
- Cytogenetic methods
- Statistical methods
- Results of their research
- Rating population level of spontaneous mutagenesis in the inhabitants of the Republic of Yemen
- CONCLUSION
- FINDINGS
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This study aimed to assess the level of spontaneous mutagenesis in the population of the Yemen Republic, particularly in areas with industrial activities like cement and plastic production. The study also sought to investigate the influence of factors like sex and smoking on the occurrence of chromosomal aberrations.
- Spontaneous mutagenesis in the Yemen Republic population
- Influence of industrial activities on chromosomal aberrations
- Sex-based differences in spontaneous mutagenesis
- Impact of smoking on chromosomal aberrations
- Environmental factors and their impact on chromosomal apparatus
Zusammenfassung der Kapitel (Chapter Summaries)
The introduction provides context by highlighting the harmful effects of environmental chemicals on DNA and chromosome damage. The study focuses on the Republic of Yemen, particularly areas with industrial production, and aims to assess the level of spontaneous mutagenesis. The materials and methods section details the cytogenetic and statistical methods used in the study, including the selection of participants, blood sample collection, cell culture techniques, and statistical analysis methods.
The results section presents the findings regarding the level of spontaneous mutagenesis in the Yemen Republic population. It analyzes the frequency of various types of chromosomal aberrations, including single fragments, paired fragments, chromosomal exchanges, and chromatid exchanges. The study also examines the influence of sex and smoking on these aberrations.
The conclusion summarizes the key findings, emphasizing the importance of evaluating spontaneous mutagenesis in developing countries with industrial activities. The findings suggest that while the overall level of spontaneous mutagenesis in the Yemen Republic population is within acceptable limits, there are statistically significant differences in the frequency of aberrations based on sex and smoking.
Schlüsselwörter (Keywords)
Spontaneous mutagenesis, chromosomal aberrations, environmental factors, industrial activities, Yemen Republic, sex differences, smoking, cytogenetic analysis, statistical analysis.
Frequently Asked Questions
What is spontaneous mutagenesis?
Spontaneous mutagenesis refers to the naturally occurring rate of genetic mutations and chromosomal aberrations in a population without specific exposure to high levels of radiation or chemicals.
What were the findings for the Yemen Republic population?
The study calculated a spontaneous mutagenesis level of 1.12 ± 0.09 per 100 cells, which is considered within normal background limits for the general population.
How does smoking affect chromosomal aberrations?
The research indicates that smoking has a statistically significant impact on the frequency of chromosomal aberrations, showing higher rates of DNA damage in smokers.
Are there sex-based differences in mutation levels in Yemen?
Yes, the study observed statistically significant differences in the frequency of chromosomal aberrations between male and female participants in the analyzed group.
What types of chromosomal aberrations were most common?
The most frequent types were single fragments (0.69%), which occurred twice as often as paired fragments (0.35%). Chromosomal and chromatid exchanges were much rarer.
- Quote paper
- Aref Alariqi (Author), 2016, Assessment level Spontaneous mutagenesis in the normal population of the Yemen Republic, Munich, GRIN Verlag, https://www.grin.com/document/321692
