Conventional synthesis of nanoparticles chemically releases toxic byproducts so there was a sudden shift towards the synthesis of nanoparticles through biological methods as it was assumed that biosynthesized nanoparticles would not be toxic. The present study aims at comparative toxicity analysis of chemically and biologically synthesized copper oxide and silver nanoparticles. Biologically synthesized copper oxide and silver nanoparticles were subjected to antimicrobial activity against five bacterial species at different dilution rate (20%, 50%, 70% and 100%). The result obtained for this was that for silver nanoparticles synthesized chemically E.coli was susceptible at 20% and 50% dilution rate. At 70% dilution rate for copper oxide nanoparticles synthesized chemically two bacterial species i.e. E.aerogens and P.aeroginosa were highly susceptible but other three species were susceptible.
Inhaltsverzeichnis (Table of Contents)
- ABSTRACT
- INTRODUCTION
- Nanoparticles synthesis
- Silver nanoparticles-
- Copper oxide nanoparticles-
- Nanoparticles asAntimicrobials
- Nanoparticles and its potentialhazards
- Hazards to human
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This study investigates the toxicity of chemically and biologically synthesized copper oxide and silver nanoparticles against bacterial species. The primary objective is to compare the antimicrobial activity of these nanoparticles synthesized through different methods and evaluate their potential for use in various applications.
- Comparative analysis of chemically and biologically synthesized nanoparticles
- Antimicrobial activity of copper oxide and silver nanoparticles against bacterial species
- Characterization of nanoparticles using UV-Vis spectroscopy and TEM analysis
- Evaluation of toxicity and potential hazards of nanoparticles
- Exploration of the potential applications of nanoparticles in various fields
Zusammenfassung der Kapitel (Chapter Summaries)
- ABSTRACT: This section provides a concise summary of the study's objectives, methods, and key findings. It highlights the comparative analysis of chemically and biologically synthesized nanoparticles and their antimicrobial activity against bacterial species.
- INTRODUCTION: This chapter introduces the concept of nanotechnology and its potential applications in various fields, including environmental remediation, industrial sectors, and healthcare. It discusses the two main approaches to nanotechnology: bottom-up and top-down processing. The chapter also introduces nanoparticles as inorganic materials with size ranging from 1 to 100 nanometers, emphasizing their importance due to their unique physical and chemical properties.
- Nanoparticles synthesis: This chapter explores different methods of nanoparticle synthesis, including chemical methods like sol-gel, precipitation, polyol, and hydrothermal synthesis. It also discusses the biological synthesis of nanoparticles using plants, fungi, bacteria, and enzymes. The chapter provides a brief overview of the potential applications of nanoparticles in various fields, illustrated by Figure 1.
- Silver nanoparticles-: This section focuses on the properties and applications of silver nanoparticles. It highlights their high thermal and electrical conductivity, making them suitable for use in electrical devices. The section also discusses their biological, physical, and chemical properties, which make them beneficial in nanobiotechnology, medical devices, and water treatment.
- Copper oxide nanoparticles-: This section discusses the properties and applications of copper oxide nanoparticles. It highlights their use in various industrial sectors, including semiconductor device manufacturing, microelectronics, solar energy conversion, batteries, gas sensors, and industrial catalysts. The section also mentions the limitations of using copper nanoparticles in atmospheric conditions due to their susceptibility to oxidation. It further discusses their applications in catalytic organic transformations, electrolysis, photolysis, and antimicrobial properties, making them suitable for use in food containers, paints, plastics, and textiles.
- Nanoparticles asAntimicrobials: This section emphasizes the use of nanoparticles in treating bacterial infections as a substitute for antibiotics. It highlights the demand for nanoparticles due to their ability to target bacterial cells and the difficulty for bacteria to develop resistance pathways against them. The section mentions the use of silver nanoparticles as antibacterial coatings for implantable devices to prevent infections and promote wound healing.
- Nanoparticles and its potentialhazards: This section explores the potential hazards associated with nanotechnology and the increasing production and use of nanoscale particles. It discusses the concerns regarding the impact of this new technology on human health, safety, and the environment. The section emphasizes the need for further research and assessment of the potential risks associated with nanoparticles, particularly those still under development.
- Hazards to human: This section introduces the concept of toxicokinetics, explaining the movement of nanoparticles through the body, their distribution, metabolic functions, and potential health hazards.
Schlüsselwörter (Keywords)
The study focuses on the synthesis, characterization, antimicrobial activity, and potential hazards of copper oxide and silver nanoparticles. It explores both chemical and biological synthesis methods, comparing their toxicity and effectiveness against bacterial species. Key terms include nanoparticles, nanotechnology, antimicrobial activity, toxicity, copper oxide, silver nanoparticles, biological synthesis, chemical synthesis, UV-Vis spectroscopy, TEM analysis, bacterial species, and potential hazards.
- Quote paper
- Dr. Pankaj Kumar Tyagi (Author), 2018, Biological and Non-Biological Synthesized Nanoparticles against Bacterial Species, Munich, GRIN Verlag, https://www.grin.com/document/1311493