Chapter on Organic synthesis contains Preparation of m-Dinitrobenzene, m-Nitroaniline, Hippuric Acid, Azlactone, phthalimide, 2,4-Dihydroxyacetophenone,Anthracene-Maleicanhydrideadduct Microwave Assisted Synthesis of Aspirin, P-Bromoacetanilide,P-Bromoaniline 2, 4, 6 Tribromoaniline; 1, 3, 5 Tribromobenzene, Aspirin, Tetrahydrocarbazole, 7-Hydroxy4-Methyl Coumarin (Umbelliferon) and Synthesis of Phenyl Indole, 7 Hydroxy-3-Methyl Flavone, 2, 5 Di hydroxy Acetophenone, 4-Chloro Toluene, Benzpinacol, 7-Hydroxy Coumarin, Maleic Anhydride, Benzophenone, Benzanilide, Vanillyl Alcohol, Ortho and Para Nitro Phenols, Acridone. In chapter two consists of Isolation of Natural product such as Isolation of Piperine from Black-pepper, Caffeine from Tea Leaves, and Cineole from Eucalyptus Leaves.Chapter three is “Drug synthesis” it mainly contains synthesis of Paracetamol, Phenytoin, Benzocaine, chlorbutol, Sulphanilamide, flourescein, Chapter four is Organic mixture analysis explained the binary as well as ternary mixture and solid- solid, solid-liquid, liquid-liquid types of mixture. While chapter five consists of spectral analysis in which UV, visible, NMR, IR etc and different types of chromatographic techniques.A special feature of this book is that the text has been illustrated with a large number of line diagrams and the data presented in the form of numerous tables for reference and comparison. It focuses, in clear and lucid language, on the basic scientific contents necessary to understand latest issues. The salient features i. Lucid and elegant style ii. Dependable information about concepts iii. Sufficient examples for practice with their spectra
Table of Contents
- Chapter 1 Organic synthesis
- 1.1 Preparation of m-Dinitrobenzene
- 1.2 Preparation of m-Nitroaniline
- 1.3 Preparation of Hippuric Acid
- 1.4 Preparation of Azlactone
- 1.5 Preparation of phthalimide
- 1.6 Preparation of 2, 4-Dihydroxyacetophenone
- 1.7 Preparation of Anthracene-Maleic anhydride adduct
- 1.8 Microwave Assisted Synthesis of Anthracene Maleic Anhydride Adduct
- 1.9 Microwave Assisted Synthesis of Aspirin
- 1.9.1 P-Bromoacetanilide
- 1.9.2 Synthesis of P-Bromoaniline
- 1.9.3 Preparation of 2, 4, 6 Tribromoaniline
- 1.9.4 Preparation of 1, 3, 5 Tribromobenzene
- 1.9.5 Preparation of Aspirin
- 1.9.6 Preparation of Tetrahydrocarbazole
- 1.9.7 7-Hydroxy4-Methyl Coumarin (Umbelliferon)
- 1.9.8 Organic Synthesis-1: 2-Phenyl Indole
- 1.9.9 Organic Synthesis-2: 7-Hydroxy-3-Methyl Flavone
- 1.10 Organic Synthesis-3: 2, 5 Di hydroxy Acetophenone
- 1.10.1 Organic Synthesis-4: 4-Chloro Toluene
- 1.10.2 Organic Synthesis-5: Benzpinacol [Photo reduction]
- 1.10.3 Organic Synthesis-6: 7-Hydroxy Coumarin
- 1.10.4 Organic Synthesis-7: Photodimerization of Maleic Anhydride
- 1.10.5 Organic Synthesis-8: Benzophenone
- 1.10.6 Organic Synthesis-9: Benzanilide
- 1.10.7 Organic Synthesis-10: Vanillyl Alcohol
- 1.10.8 Organic Synthesis-11 Ortho and Para Nitro Phenols
- 1.10.9 Organic Synthesis-12: Acridone
- Chapter 2 Isolation of Natural product
- 2.0 Isolation of Piperine from Black-pepper
- 2.1 Isolation of Caffeine from Tea Leaves
- 2.2 Isolation of Cineole from Eucalyptus Leaves
- Chapter 3 Drug synthesis
- 3.0 synthesis of Paracetamol
- 3.1 synthesis of Phenytoin
- 3.2 synthesis of Benzocaine
- 3.4 synthesis of Synthesis of chlorbutol
- 3.5 synthesis of Sulphanilamide
- 3.6 synthesis of flourescein
- Chapter 4 Organic mixture analysis
- 4.0 Analysis of Organic Binary and Ternary Mixture Analysis
- 4.1 Separation reagent
- 4.2 Solubility procedure
- 4.3 Separation procedure
- 4.4 Solid-liquid or liquid-liquid mixture
- 4.5 Binary mixture
- 4.6 Ternary mixture
- 4.7 Qualitative Analysis of Organic Compounds
- 4.8 Functional Group Analysis: Analysis of Carboxylic Acids
- 4.9 Derivative: Amide & Anilide
- Chapter 5 Spectral analysis
Objectives and Key Themes
This book aims to provide a comprehensive practical guide for M.Sc. chemistry students, covering essential organic and inorganic chemistry techniques. It bridges the gap between theoretical knowledge and practical application, equipping students with the skills needed for their professional careers. * Organic Synthesis Techniques * Isolation of Natural Products * Drug Synthesis * Organic Mixture Analysis * Spectral and Chromatographic AnalysisChapter Summaries
Chapter 1 Organic synthesis: This chapter provides a detailed guide to various organic synthesis procedures. It covers the preparation of a wide range of compounds, including m-Dinitrobenzene, m-Nitroaniline, Hippuric Acid, Azlactone, phthalimide, and many others. The chapter emphasizes both traditional and modern synthetic methods, such as microwave-assisted synthesis, illustrating the practical applications and significance of each reaction. The numerous examples presented provide a comprehensive understanding of diverse synthetic strategies and reaction mechanisms within organic chemistry. Chapter 2 Isolation of Natural product: This chapter focuses on the isolation of key natural products from their natural sources. It details the procedures for isolating Piperine from black pepper, Caffeine from tea leaves, and Cineole from eucalyptus leaves. The chapter emphasizes the techniques involved in extraction, purification, and identification of these compounds, providing practical experience in natural product chemistry. The techniques are vital for understanding the source and application of many important bioactive compounds. Chapter 3 Drug synthesis: This chapter delves into the synthesis of several important pharmaceutical compounds. It outlines the procedures for preparing Paracetamol, Phenytoin, Benzocaine, Chlorbutol, Sulphanilamide, and Fluorescein. The chapter provides a detailed description of the reaction mechanisms, reaction conditions, and purification techniques for each synthesis, offering crucial insight into medicinal chemistry practices. This provides students with practical expertise in the creation of important pharmaceutical agents. Chapter 4 Organic mixture analysis: This chapter focuses on the analysis of organic mixtures, covering both binary and ternary mixtures of various types (solid-solid, solid-liquid, liquid-liquid). It details procedures for separation, purification, and identification of components within these mixtures. The chapter also provides a detailed guide to qualitative analysis of organic compounds, focusing on functional group analysis, with specific examples such as carboxylic acid analysis and derivative formation (amide & anilide). This chapter is crucial for understanding analytical techniques within organic chemistry.Keywords
Organic synthesis, natural product isolation, drug synthesis, organic mixture analysis, spectral analysis, chromatographic techniques, practical chemistry, m-Dinitrobenzene, m-Nitroaniline, Hippuric Acid, Azlactone, phthalimide, Piperine, Caffeine, Cineole, Paracetamol, Phenytoin, Benzocaine, Chlorbutol, Sulphanilamide, Fluorescein, UV, visible, NMR, IR spectroscopy.
Frequently Asked Questions: Comprehensive Language Preview of Organic Chemistry
What is the purpose of this book?
This book serves as a comprehensive practical guide for M.Sc. chemistry students. It aims to bridge the gap between theoretical knowledge and practical application in organic and inorganic chemistry, equipping students with essential skills for their future careers.
What topics are covered in this book?
The book covers five key areas: Organic Synthesis Techniques, Isolation of Natural Products, Drug Synthesis, Organic Mixture Analysis, and Spectral and Chromatographic Analysis. Each area is explored in detail through various chapters and practical examples.
What are the key themes explored in the book?
The key themes revolve around practical application of chemistry principles. The book emphasizes hands-on experience through detailed procedures and examples for various organic synthesis methods, natural product isolation, drug preparation, organic mixture analysis and spectroscopic techniques.
What specific organic synthesis procedures are detailed in the book?
Chapter 1 provides detailed instructions for numerous organic synthesis procedures. Examples include the preparation of m-Dinitrobenzene, m-Nitroaniline, Hippuric Acid, Azlactone, phthalimide, 2, 4-Dihydroxyacetophenone, Anthracene-Maleic anhydride adduct, Aspirin, Tetrahydrocarbazole, 7-Hydroxy4-Methyl Coumarin (Umbelliferon), 2-Phenyl Indole, 7-Hydroxy-3-Methyl Flavone, 2, 5 Di hydroxy Acetophenone, 4-Chloro Toluene, Benzpinacol, 7-Hydroxy Coumarin, and many more. Microwave-assisted synthesis techniques are also included.
How are natural product isolations covered?
Chapter 2 focuses on the isolation of natural products. Specific examples include isolating Piperine from black pepper, Caffeine from tea leaves, and Cineole from eucalyptus leaves. The chapter details extraction, purification, and identification techniques.
Which drugs are covered in the drug synthesis section?
Chapter 3 details the synthesis of several important drugs, including Paracetamol, Phenytoin, Benzocaine, Chlorbutol, Sulphanilamide, and Fluorescein. The procedures cover reaction mechanisms, conditions, and purification techniques.
What is covered in the organic mixture analysis chapter?
Chapter 4 focuses on analyzing organic mixtures, both binary and ternary (solid-solid, solid-liquid, liquid-liquid). It covers separation, purification, and identification procedures, along with qualitative analysis, functional group analysis (e.g., carboxylic acids), and derivative formation (amides & anilides).
What types of spectral analysis are included?
While Chapter 5 on Spectral Analysis is briefly mentioned, the content is not detailed in the provided preview. However, the keywords list mentions UV, visible, NMR, and IR spectroscopy as being covered.
Who is the target audience for this book?
This book is primarily intended for M.Sc. chemistry students seeking a comprehensive, practical guide to organic and inorganic chemistry techniques.
What are the key words associated with this book?
Key words include: Organic synthesis, natural product isolation, drug synthesis, organic mixture analysis, spectral analysis, chromatographic techniques, practical chemistry, and the names of specific compounds synthesized (e.g., m-Dinitrobenzene, Paracetamol, etc.).
- Quote paper
- Prof. Amrut Gaddamwar (Author), Prof. P. R. Rajput (Author), 2013, Organic and Inorganic Practical Chemistry, Munich, GRIN Verlag, https://www.grin.com/document/213967
