Stereochemistry - An Introduction is the introduction about the Stereochemistry it includes, Axial Chirality, Atropisomers, Planar Chirality, Helical Chirality, Cyclosteroisomerism and Reteroenantio Isomerism.
Inhaltsverzeichnis (Table of Contents)
- AXIAL CHIRALITY
- ATROPISOMERS
- PLANAR CHIRALITY
- HELICAL CHIRALITY
- CYCLOSTEROISOMERISM
- RETEROENANTIO ISOMERISM
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This book, "Stereochemistry-An Introduction", provides a comprehensive overview of the fundamental principles and concepts of stereochemistry. It aims to introduce readers to the various types of chirality, focusing on the structural features and properties that give rise to enantiomers and diastereomers.
- Axial chirality and its manifestation in allenes and spiranes
- Atropisomerism and its relationship to restricted rotation
- Planar chirality and its occurrence in various molecular systems
- Helical chirality and its application in understanding natural and synthetic compounds
- Cyclosteroisomerism and its impact on conformational analysis
Zusammenfassung der Kapitel (Chapter Summaries)
- Chapter 1: Axial Chirality: This chapter introduces the concept of axial chirality, explaining how elongation of a tetrahedron along an axis leads to a chiral center. It delves into the structural features of allenes, biphenyls, and spiranes that exhibit this type of chirality.
- Chapter 2: Atropisomers: This chapter focuses on atropisomers, which are stereoisomers that arise due to hindered rotation around a single bond. It explores the factors influencing atropisomerism and the implications for molecular properties and reactivity.
- Chapter 3: Planar Chirality: This chapter discusses planar chirality, a type of chirality that arises from a molecule's planar structure. It examines various examples of planar chiral molecules, including those with restricted rotation and those with specific substituent arrangements.
- Chapter 4: Helical Chirality: This chapter explores helical chirality, a type of chirality arising from the helical arrangement of atoms in a molecule. It examines how helical chirality is found in natural and synthetic compounds and its impact on their properties and biological activity.
- Chapter 5: Cyclosteroisomerism: This chapter delves into cyclosteroisomerism, a type of chirality associated with the cyclic structure of molecules. It discusses the influence of ring size, substituent positions, and conformational flexibility on the stereochemistry of cyclic compounds.
Schlüsselwörter (Keywords)
The core concepts and key terms covered in this book include axial chirality, atropisomerism, planar chirality, helical chirality, cyclosteroisomerism, enantiomers, diastereomers, allenes, spiranes, biphenyls, hindered rotation, and conformational analysis.
Frequently Asked Questions
What is axial chirality?
Axial chirality occurs when a molecule lacks a chiral center but has an axis about which a set of substituents is held in a spatial arrangement that is not superimposable on its mirror image, common in allenes.
What are atropisomers?
Atropisomers are stereoisomers resulting from hindered rotation about a single bond where the steric strain barrier to rotation is high enough to allow for the isolation of the individual conformers.
How does planar chirality arise?
Planar chirality results from the arrangement of out-of-plane groups with respect to a reference plane within the molecule, often seen in certain cyclophanes or substituted ferrocenes.
What is helical chirality?
Helical chirality (or helicity) refers to molecules that have a screw-like shape, like helicenes, which can exist in left-handed or right-handed forms.
What is the difference between enantiomers and diastereomers?
Enantiomers are non-superimposable mirror images of each other, while diastereomers are stereoisomers that are not mirror images, often having different physical properties.
- Citar trabajo
- Purvesh Shah (Autor), 2012, Stereochemistry. An Introduction, Múnich, GRIN Verlag, https://www.grin.com/document/272561
