Diabetes mellitus is a clinical metabolic syndrome, which has been resulted from the malfunction or insufficiency of insulin production. Diabetes is the major threat to the people in developing and developed country. Prolonged diabetic condition can affect organs and synthetic drug if consumed by the patient can cause side-effects and impaired immune system. The synthetic medicine used for the treatment of diabetes is usually costlier, create side-effects and do not ensure complete recovery from the disorder but on the other hand, medicinal plants create a great impact in the human immune system.
The medicinal plant produces a variety of chemical substances which shows significant therapeutic properties. This study highlights the potential anti-diabetic significance and phytochemical activity of different varieties Piper nigrum (Black pepper) and different strategies used for the assessment of these activities. The piperaceae family consist of 12 genera and more than 1400 species and is one of the largest families and widely distributed across the tropical and sub-tropical regions and over the high ranges of Andes and Sub Himalayas. Piper species naturally have multi-dimensional affect on various parts of the body often mentioned as antipyretic, diuretic, aphrodisiac, immune- stimulant and antioxidant, hepatoprotective, digestive, antiseptic and anti-diabetic. Phytochemical analysis of Methanol and Petroleum -ether extracts was carried out and different plant parts were collected from different districts across Kerala.
Phytochemical which is identified from Piper nigrum present an exciting opportunity for the development of new type of therapeutics for diabetes mellitus. Some anti-diabetic plants exert their action by stimulating the function or number of beta cells and thus increasing insulin production with least side effects. Further investigations are required and more attention should be drawn to explore the biological activity of hundreds of traditionally used plants. Both in-vivo and in-vitro assessment is necessary for the assessment of anti-diabetic properties from the natural resources.
Inhaltsverzeichnis (Table of Contents)
- Table of contents
- Table of figures
- Table of tables
- List of abbreviations
- Phytochemical and anti-diabetic activities of different plant part among black pepper (Piper nigrum) varieties in comparison with Piper longum and Piper betel: an overview
- Abstract
- 1. Introduction
- 1.1 Objectives
- 1.2 Scope of the study
- 1.3 Taxonomical classification: Piper nigrum
- 1.4 Taxonomical classification: Piper betle Linn.
- 1.5 Taxonomical classification: Piper longeum Linn
- 2. Review of literature
- 2.1 Uses and importance
- 3. Hypothesis
- 4. Materials and Methods
- 4.1 Study area
- 4.2 Sample collection and processing
- 4.3 Experiment design
- 4.3.1 Experiment
- 4.4 Phytochemical screening
- 4.4.1 Test for tannins
- 4.4.2 Test for flavonoids
- 4.4.3 Test for terpenoids
- 4.4.4 Test for saponins
- 4.4.5 Test for phlobatannins
- 4.4.6 Test for carbohydrates
- 4.4.7 Test for glycosides
- 4.4.8 Test for coumarins
- 4.4.9 Test for alkaloids
- 4.4.10 Test for phenols
- 4.4.11 Test for emodins
- 4.4.12 Test for anthraquinones
- 4.4.13 Test for anthocyanins
- 4.4.14 Test for leucoanthocyanins
- 4.5 Determination of the changes in glucose level (Anthrone method)
- 4.6 Determination of the changes in glucose level (Benedicts test)
- 4.7 Statistical analysis
- 5. Results and discussion
- 5.1 Phytochemical screening
- 5.2 Glucose reduction tests
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This research paper examines the anti-diabetic potential and phytochemical composition of various Piper species, specifically focusing on different varieties of black pepper (Piper nigrum), Piper longum, and Piper betel. The study aims to compare the phytochemical profile and glucose-lowering activity of these plants, exploring their potential for developing alternative treatments for diabetes mellitus.
- Phytochemical analysis of Piper species for bioactive compounds
- Comparison of anti-diabetic activity of different plant parts
- Investigation of glucose-lowering effects in different varieties of black pepper
- Exploring the potential of Piper species as a source for antidiabetic drugs
- Highlighting the need for further in-vitro and in-vivo research
Zusammenfassung der Kapitel (Chapter Summaries)
- Introduction: The paper introduces black pepper (Piper nigrum), Piper betel, and Piper longum as potential sources of anti-diabetic compounds. It discusses the importance of traditional medicines in global healthcare and the increasing prevalence of diabetes mellitus. The objectives of the study are outlined, along with the scope and taxonomical classification of the Piper species investigated.
- Review of Literature: This section reviews existing research on the medicinal properties of Piper species, highlighting their use in traditional medicine systems and their potential for treating various ailments including diabetes. It discusses the importance of phytochemical analysis and the role of specific bioactive compounds in antidiabetic activity.
- Materials and Methods: This chapter describes the methodology used in the study, including the study area (Kerala, India), sample collection and processing, experimental design, phytochemical screening methods, and glucose reduction tests. The specific varieties of Piper species investigated are detailed, along with the solvents and concentrations used.
Schlüsselwörter (Keywords)
The primary keywords and focus topics of this paper encompass anti-diabetic activity, phytochemical analysis, Piper species, black pepper, Piper nigrum, Piper longum, Piper betel, traditional medicine, and alternative therapies. The research delves into the potential of these plants as sources for developing new and effective treatments for diabetes mellitus.
- Quote paper
- Dr. Prem Jose Vazhacharickal (Author), Sajeshkumar N.K (Author), Jiby John Mathew (Author), Annie Babu (Author), 2017, Phytochemical and anti-diabetic activities of different plant part extracts among black pepper (Piper nigrum) varieties in comparison with Piper longum and Piper betel, Munich, GRIN Verlag, https://www.grin.com/document/370191
