A large number of drugs and biologically relevant molecules contain heterocyclic systems. Often the presence of hetero atoms or groupings imparts preferential specificities in their biological responses. Amongst the heterocyclic systems, compounds containing hetero atoms such as nitrogen and/or sulfur e.g., thiazolidinones, benzothiazoles, triazines, etc. have great importance due to their diverse biological activity.
Finding numerous biological importances of these ring systems, it is worth to study such building blocks for better understanding of medicinal chemistry as well as synthetic organic chemistry involving the synthesis of such different biologically active nitrogen- and/or sulfur-containing heterocyclic moieties like substituted benzothiazoles, triazines, pyrrolidine, azetidinones, pyridines, oxazoles, thiazoles, Schiff bases, etc.
In view of such facts, the present book deals with the review of the biologically important heterocyclic moiety benzothiazole.
Inhaltsverzeichnis (Table of Contents)
- Introduction
- About Benzothiazole
- Synthesis from arylthioureas
- Synthesis from p-toluidine
- Reported literature of benzothiazole
- References
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This book provides a comprehensive review of the biologically important heterocyclic moiety benzothiazole. It explores the synthesis and reported literature of this compound, highlighting its diverse biological activities and potential applications in medicinal chemistry.
- The significance of heterocyclic systems in biologically relevant molecules
- The importance of nitrogen and sulfur-containing heterocycles in medicinal chemistry
- The diverse biological activities of benzothiazoles
- The synthesis of benzothiazoles from various starting materials
- A review of relevant literature on benzothiazoles
Zusammenfassung der Kapitel (Chapter Summaries)
- Introduction: This chapter introduces the concept of heterocyclic systems in biologically relevant molecules and highlights the importance of nitrogen and sulfur-containing heterocycles, such as benzothiazoles, in medicinal chemistry.
- About Benzothiazole: This chapter discusses the synthesis of benzothiazole from arylthioureas and p-toluidine. It covers different synthetic methods and their implications in the production of this important heterocycle.
- Reported literature of benzothiazole: This chapter delves into the reported literature on benzothiazole, reviewing its diverse biological activities, potential applications, and research findings related to its properties and synthesis.
Schlüsselwörter (Keywords)
Benzothiazole, heterocyclic systems, medicinal chemistry, biological activity, synthesis, nitrogen-containing heterocycles, sulfur-containing heterocycles, arylthioureas, p-toluidine, literature review.
Frequently Asked Questions
What is Benzothiazole?
Benzothiazole is a biologically important heterocyclic moiety containing nitrogen and sulfur atoms, widely studied for its diverse pharmacological activities.
Why are heterocyclic systems important in medicine?
Heterocyclic systems often impart specific biological responses in drugs. Those containing nitrogen and sulfur, like benzothiazoles, are crucial for developing various biologically active molecules.
How can Benzothiazole be synthesized?
Common synthetic routes include synthesis from arylthioureas and from p-toluidine, as discussed in the book's review of organic chemistry methods.
What types of biological activities are associated with Benzothiazoles?
Benzothiazoles are known for a wide range of biological responses, making them essential scaffolds for research in medicinal chemistry and drug design.
What other heterocyclic compounds are related to this study?
The study also references related moieties such as thiazolidinones, triazines, pyrrolidine, azetidinones, and Schiff bases.
- Quote paper
- Dr. Faiyazalam Shaikh (Author), Dr. Navin Patel (Author), 2009, Benzothiazole. Biologically useful and important scaffold, Munich, GRIN Verlag, https://www.grin.com/document/426873
