The work focuses on the analysis of the flow fields in the Food and Drug Administrations (FDA) 'Critical Path' benchmark blood pump. The CAD model of the pump is an opensource material, so the thesis works started with the mesh generation. A block-structured hexahedral mesh has been created using ANSYS ICEM CFD 15.0. An unsteady (URANS) incompressible blood flow simulation has been performed using k-ω SST turbulence model, with one of the operating conditions prescribed by the experimental literature. The simulations were performed using ANSYS CFX 19.1 solver. The validated results for the flow field show promising results in the blade passage region and the diffuser regions but the pressure head obtained has some discrepancies which were analyzed and justified. In addition, a study on hemolysis prediction using Power Law was performed, and the blood damage values of the benchmark blood pump were calculated for the stress-based model in the Eulerian approach.
The role of Computational Fluid Dynamics (CFD) in the biomedical field has increased a lot in recent years. The problems related to biocompatibility in medical and biological industries capture the attention of CFD engineers. One such biocompatible device is a Ventricular Assist Device (VAD). The development phase of VAD's associates CFD to make it more robust. VADs generally incorporated with blood pumps, so it is essential to examine the dynamics of the blood flow in the pump and also to analyze the damages concerned with the blood cells.
The U.S. Food and Drug Administration (FDA)and the Center of Devices and Radiological Health (CDRH) have sponsored certain CFD'round-robins' to validate the efficiency of computer simulations in biomedical applications. The ‘Computational round-robin #2’ concerns with a 'Critical Path' benchmark blood Pump.
Inhaltsverzeichnis (Table of Contents)
- Introduction
- Ventricular Assist Device
- History of VADs
- Operating Conditions for VAD
- Role of Computational Fluid Dynamics
- Literature Review
- Blood
- Red Blood Cells
- Blood Rheology
- Blood damage
- Numerical Hemolysis Prediction
- Blood
- Description of Turbulence Modeling
- RANS/URANS
- Shear Stress Transport model
- RANS/URANS
- Experimental Study
- Pre-Processing
- Structure of FDA blood pump
- Mesh Information
- Mesh Overview
- Mesh Generation
- Computation
- Results and Discussion
- Convergence
- Pressure Head
- Flow Field
- Wall Shear Stress and Hemolysis Comparison
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This master thesis aims to analyze the flow fields in the FDA's "Critical Path" benchmark blood pump, contributing to the advancement of Computational Fluid Dynamics (CFD) in biomedical applications. The work focuses on validating the efficiency of computer simulations for the development and optimization of Ventricular Assist Devices (VADs), specifically blood pumps.
- CFD in Biomedical Applications
- Blood Pump Design and Optimization
- Hemolysis Prediction
- Computational Modeling of Blood Flow
- Validation of CFD Simulations
Zusammenfassung der Kapitel (Chapter Summaries)
The thesis begins with an introduction to VADs, their history, and the role of CFD in their development. Chapter 2 provides a literature review on blood, blood rheology, blood damage, and numerical hemolysis prediction. Chapter 3 details the turbulence modeling used, specifically the RANS/URANS approach and the Shear Stress Transport model. The pre-processing stage, including the structure of the FDA blood pump and the mesh generation process, is outlined in Chapter 5. Chapter 6 discusses the computational methods used. Finally, Chapter 7 presents the results and discussion of the simulation, including convergence, pressure head, flow field analysis, and hemolysis prediction.
Schlüsselwörter (Keywords)
The key terms and concepts explored in this thesis include Computational Fluid Dynamics (CFD), Ventricular Assist Device (VAD), blood pump, block-structured hexahedral mesh, URANS, k-w SST, hemolysis, Power Law, stress-based model, and Eulerian approach.
- Quote paper
- Krishnaraj Narayanaswamy (Author), 2019, Numerical Flow Simulation in FDA's "Critical Path" benchmark blood pump, Munich, GRIN Verlag, https://www.grin.com/document/915240
