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Deductive, Systematic Signal Validation as Method for Efficacy Improvement in Pharmaco- and Chemo-Vigilance

1. Deutscher Kongress für Patientensicherheit bei medikamentöser Therapie, April 19th – 20th, Congresshalle, Saarbrücken, Germany - R. Arno Wess, Joseph Gut and Robert Dannecker


Redacción Científica, 2005

1 Páginas, Calificación: Keine


Resumen o Introducción

Signal Validation can lead Vigilance
Just single ADRs relating the known benzene – toxicologic endpoints (leukemia, breast cancer) and these substances are worth to be investigated completely, since they enable risk assessments based on predisposition and epidemiology much earlier. The need of intelligence tools to deal with such heterogeneous data is obvious. The paradoxical situation that often arises is characterized by information overload but knowledge deficiency, and the need for intellectual involvement in information assimilation4. IT tools for intelligence are designed to assess risks in situations when only bits and pieces of knowledge are available but the situation forces to find the trace of future and past events (like it is the case in criminology, counter-terrorism, and military intelligence).

Detalles

Título
Deductive, Systematic Signal Validation as Method for Efficacy Improvement in Pharmaco- and Chemo-Vigilance
Subtítulo
1. Deutscher Kongress für Patientensicherheit bei medikamentöser Therapie, April 19th – 20th, Congresshalle, Saarbrücken, Germany - R. Arno Wess, Joseph Gut and Robert Dannecker
Curso
1. Deutscher Kongress für Patientensicherheit bei medikamentöser Therapie, Congresshalle, Saarbrücken, Germany
Calificación
Keine
Autor
Año
2005
Páginas
1
No. de catálogo
V125407
ISBN (Ebook)
9783640312337
Tamaño de fichero
893 KB
Idioma
Inglés
Notas
An example on Benzene Toxicity and crossing metabolic pathways is given.
Palabras clave
Bezene toxicity, Signal Validation, Pharmacovigilance, Translational Medicine, Read-Across, Crossing pathways, Benzene toxicity, In silico
Citar trabajo
Ralf Arno Wess (Autor), 2005, Deductive, Systematic Signal Validation as Method for Efficacy Improvement in Pharmaco- and Chemo-Vigilance, Múnich, GRIN Verlag, https://www.grin.com/document/125407

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Título: Deductive, Systematic Signal Validation as Method for Efficacy Improvement in Pharmaco- and Chemo-Vigilance


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