The Student Conference on Medical Engineering Science is an annual event at the BioMedTec Science Campus Luebeck. The Student Congress is organized by the University of Lübeck and Medisert and is supported by NORGENTA, the life science cluster agency in north Germany. Master students of programs related to medical engineering science present results of their recent research projects.
Die Studierendentagung Medizintechnik findet jährlich auf dem BioMedTec Wissenschaftscampus Lübeck statt. Der Kongress wird von der Universität zu Lübeck und Medisert organisiert und von der norddeutschen Life-Science-Clusteragentur NORGENTA unterstützt. Studierende in Masterprogrammen der Medizintechnik und der Lebenswissenschaften präsentieren die Ergebnisse ihrer jüngsten Forschungsprojekte.
Inhaltsverzeichnis (Table of Contents)
:- Preface and Acknowledgements
- Biochemical Optics I
- Improving the stability of an interferometry-based photoacoustic detection
- Implementation of a reconstruction algorithm for Photoacoustic Tomography
- Light transmission measurements and beam size quantification in porcine eyes
- Parameter optimization for power controlled retinal photocoagulation
- Biochemical Optics II
- Imaging of heat and chemical burn affected skin ex vivo with coherent anti-stokes Raman (CARS) microscopy
- Variable, computer-controlled attenuator for use in a time-gated optical scanning system
- Development and validation of a measuring setup to determine the transmittance of the illumination system of endoscopes
- Biochemical Physics
- Effect of substrate stiffness on photodynamic therapy sensitivity of various glioma cell lines in vitro
- Photosensitizer delivery by liposomes
- Investigation of human skin permeability to zinc oxide nanoparticles formulated as sunscreen
- Measurement of concentrations of photoreactive liquids with high scattering using a differential polarimeter
- Evaluation of the usability of the metadynamics tool PLUMED2
- Biomedical Engineering I
- Characterisation of Pyroelectric Detectors for the Measurement of Medical and Safety-Relevant Gases
- Design and implantation of a test bed to separate different drugs in multi-infusion system using gas bubbles
- Flow Optimisation through Porous Ceramic Throttle
- Compressive behaviour and isotropy of short-fiber-filled epoxy cylinders as alternative test material for cortical bone
- Evaluation of needle deformation during brachytherapy
- Biomedical Engineering II
- Practice of reprocessing medical single-use devices in Schleswig-Holstein
- Software testing as an important component in the development of medical devices
- Draft of a multichannel electromyography amplifier circuit with monopolar lead for hand prostheses control
- Signal Processing
- Overcoming electrodes shift variances in multi-channel surface EMG recordings for prosthetic controlling
- Coil Geometry Optimization and Implementation of a Field Generator for Magnetic Particle Spectroscopy
- Signal Chain Optimization in Magnetic Particle Imaging
- Sparse Representation of Motion-Vector Fields using the Wavelet Transform
- Dictionary learning for sparse image representation with K-SVD algorithm
- VimbEye Exhibition Demo – an AVT machine vision camera application for eye-blink visualisation
- Imaging and Image Computing I
- Localization of Heart Reference Point of a Lying Patient with Microsoft Kinect Sensor
- Automatic image quality assessment of head MRI study data
- Development and Validation of a Tool for Pulse Wave Velocity Measurements in MRI Phase Contrast Data
- Motion correction for MRI exploiting sparsity
- Imaging and Image Computing II
- Analysis of Streamline Intensity Variances for Pulmonary Emboli Visualization in CTA Images
- Evaluation of Methods for Automatic Fish Segmentation
- An Algorithm for Automated Model Generation of in Vitro Cell Images
- Subtraction Imaging on Double Inversion Recovery Images for Cortical Lesion Detection in Patients with Multiple Sclerosis
- Magnetic Resonance Imaging I
- Visualizing Microscopic Hemorrhages with Susceptibility-Weighted Imaging (SWI) for Forensic Applications
- Automatic Image Quality Assessment of Head MRI Study Data
- Motion Correction for MRI Exploiting Sparsity
- Development and Validation of a Tool for Pulse Wave Velocity Measurements in MRI Phase Contrast Data
- Magnetic Resonance Imaging II
- Connection between structural and functional Connectivity: A Magnetic Resonance Study
- Generation of an Accurate Tetrahedral Model of a Brain with Chronic Stroke Lesions for TMS and tDCS Field Calculations
- Spectral editing at 7 T: In vivo GABA separation in mouse brain
- Radiosurgery beyond cancer: Real-time tracking and treatment planning for non-invasive treatment of cardiac arrhythmia
- LUMEN
- Drug release from bone implants: a phenomenological modeling approach
- Modeling diffusion of gentamicin eluted from a coated intramedullary nail
- Investigation of particle dynamics near the endothelial glycocalyx by multi focus FCS
- Holographic detection for non-contact Photoacoustic Tomography
- A physical model of perfused pulsating tissue compartments – Design concept
- Measuring the oxygen content of the cerebral efferent vessels
- Insight in Scanner Construction for a Dynamical Field Free Line for Magnetic Particle Imaging
- Experimental Evaluation & Optimization of a UWB Localization System for Medical Applications
- A System for In-Ear Pulse Wave Measurements
- Signal Chain Optimization in Magnetic Particle Imaging
- Sparse Representation of Motion-Vector Fields using the Wavelet Transform
- Draft of a multichannel electromyography amplifier circuit with monopolar lead for hand prostheses control
- Design Change of a Flow Sensor for Medical Applications – Engineering Tests for System Integration
- Construction and Optimization of a Bidirectional Transducer to Treat Hearing Loss
- Design, Development and Comparison of two Different Measurement Devices for Time-Resolved Determination of Phase Shifts of Bioimpedances
- A System for Multi-Modal Assessment of Cardiovascular Parameters – Design and Measurements
- Characterisation of Pyroelectric Detectors for the Measurement of Medical and Safety-Relevant Gases
- Design and implantation of a test bed to separate different drugs in multi-infusion system using gas bubbles
- Flow Optimisation through Porous Ceramic Throttle
- Compressive behaviour and isotropy of short-fiber-filled epoxy cylinders as alternative test material for cortical bone
- Evaluation of needle deformation during brachytherapy
- Light transmission measurements and beam size quantification in porcine eyes
- Parameter optimization for power controlled retinal photocoagulation
- Imaging of heat and chemical burn affected skin ex vivo with coherent anti-stokes Raman (CARS) microscopy
- Variable, computer-controlled attenuator for use in a time-gated optical scanning system
- Development and validation of a measuring setup to determine the transmittance of the illumination system of endoscopes
- Effect of substrate stiffness on photodynamic therapy sensitivity of various glioma cell lines in vitro
- Photosensitizer delivery by liposomes
- Investigation of human skin permeability to zinc oxide nanoparticles formulated as sunscreen
- Measurement of concentrations of photoreactive liquids with high scattering using a differential polarimeter
- Evaluation of the usability of the metadynamics tool PLUMED2
- Improving the stability of an interferometry-based photoacoustic detection
- Implementation of a reconstruction algorithm for Photoacoustic Tomography
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
: This collection of abstracts represents the work presented at the 3rd Student Conference on Medical Engineering Science, held in Lübeck, Germany in March 2014. The conference brought together master students from the BioMedTec Science Campus Lübeck to present their research in the field of medical engineering. The abstracts cover a wide range of topics, from the development of new imaging techniques to the improvement of existing medical devices. The main objectives of the conference were to: * Provide a platform for students to present their research findings * Foster collaboration and knowledge exchange between students and researchers * Highlight the importance of medical engineering in addressing real-world medical challenges * Inspire future generations of medical engineers The following key themes emerged from the abstracts: * **Biomedical Optics**: This theme encompasses the use of light and ultrasound for medical imaging and therapy. Several abstracts focus on photoacoustic imaging, a technique that combines the advantages of both modalities. Other abstracts investigate the use of light for retinal photocoagulation and the development of new optical methods for sensing and analyzing chemical compounds. * **Biomedical Engineering**: This theme focuses on the development and improvement of medical devices. Abstracts in this theme address topics like the design and construction of implantable devices, flow regulation for drug delivery systems, and the reprocessing of medical single-use devices. * **Signal Processing**: This theme covers the processing and analysis of medical signals. Several abstracts explore methods for improving the quality of EMG signals for prosthetic control, optimizing signal chains in Magnetic Particle Imaging (MPI), and developing sparse representation methods for motion-vector fields. * **Imaging and Image Computing**: This theme examines the use of computer algorithms and techniques for medical image analysis and processing. Abstracts in this theme address topics like the automatic detection of pulmonary emboli in CT angiography images, the segmentation of fish images, and the visualization of microscopic hemorrhages in brain samples using susceptibility-weighted imaging (SWI). * **Magnetic Resonance Imaging**: This theme is dedicated to the use of MRI for medical diagnosis and research. Abstracts explore the development of new tools for measuring pulse wave velocity, the analysis of structural and functional connectivity in the brain, and the visualization of brain lesions in patients with multiple sclerosis.Zusammenfassung der Kapitel (Chapter Summaries)
:- **Biochemical Optics I**: This chapter focuses on the development of optical methods for medical imaging and therapy. Several abstracts investigate the use of photoacoustic imaging, a non-invasive imaging technique with high potential in medicine. The authors explore the use of interferometry for photoacoustic detection, develop reconstruction algorithms, and investigate the transmission and beam size of laser light in porcine eyes.
- **Biochemical Optics II**: This chapter continues to explore the use of light and ultrasound for medical applications. The authors present an innovative system for variable and computer-controlled attenuation of light, discuss the use of coherent anti-Stokes Raman scattering (CARS) microscopy for imaging skin damage, and validate a new measurement setup for determining the transmittance of endoscopes.
- **Biochemical Physics**: This chapter focuses on the effects of substrate stiffness on cell behavior and the delivery of photosensitizers by liposomes. The authors investigate the impact of substrate stiffness on the sensitivity of glioma cells to photodynamic therapy, compare different liposomal formulations for photosensitizer delivery, and examine the permeability of human skin to zinc oxide nanoparticles formulated as sunscreen. They also evaluate the usability of the metadynamics tool PLUMED2 for molecular simulations.
- **Biomedical Engineering I**: This chapter explores the development and improvement of medical devices. The authors present the characterization of pyroelectric detectors for gas measurement, the design of a test bed for drug separation in infusion systems, and the optimization of flow through porous ceramic throttles. They also investigate the mechanical behavior of short-fiber-filled epoxy cylinders as a potential alternative test material for cortical bone and analyze the deformation of brachytherapy needles during insertion.
- **Biomedical Engineering II**: This chapter focuses on the reprocessing of medical single-use devices (SUDs) and software testing for medical devices. The authors investigate the current practice of reprocessing SUDs in Schleswig-Holstein, analyze the impact of the upcoming MDD regulation, and emphasize the importance of software testing in medical device development. They also present a draft for a multichannel electromyography amplifier circuit with monopolar lead for hand prostheses control.
- **Signal Processing**: This chapter covers a variety of topics related to the processing and analysis of medical signals. The authors present methods for overcoming electrode shift variances in multi-channel surface EMG recordings, optimizing coil geometry for magnetic particle spectroscopy, and optimizing signal chains in Magnetic Particle Imaging (MPI). They also investigate sparse representation methods for motion-vector fields using the wavelet transform and develop dictionary learning algorithms for sparse image representation.
- **Imaging and Image Computing I**: This chapter explores the use of computer algorithms and techniques for medical image analysis and processing. The authors present a method for localizing the heart reference point of a lying patient using the Microsoft Kinect sensor, develop a tool for automatic image quality assessment of head MRI data, and explore motion correction techniques for MRI exploiting sparsity. They also present a tool for measuring pulse wave velocity in MRI phase contrast data.
- **Imaging and Image Computing II**: This chapter continues the focus on medical image analysis and processing. The authors investigate the use of streamline intensity variances for visualizing pulmonary emboli in CT angiography images, evaluate methods for automatic fish segmentation, and develop an algorithm for automated model generation of in vitro cell images. They also explore the use of subtraction imaging on double inversion recovery (DIR) images for detecting cortical lesions in patients with multiple sclerosis.
- **Magnetic Resonance Imaging I**: This chapter is dedicated to the use of MRI for medical diagnosis and research. The authors present a method for visualizing microscopic hemorrhages with susceptibility-weighted imaging (SWI) for forensic applications, develop a tool for automatic image quality assessment of head MRI data, and explore motion correction techniques for MRI exploiting sparsity. They also present a tool for measuring pulse wave velocity in MRI phase contrast data.
- **Magnetic Resonance Imaging II**: This chapter continues to explore the use of MRI for medical diagnosis and research. The authors investigate the connection between structural and functional connectivity in the brain using fMRI and DWI data, and develop methods for generating accurate tetrahedral models of the brain with chronic stroke lesions for TMS and tDCS field calculations. They also investigate spectral editing at 7T for in vivo GABA separation in mouse brain and explore the use of radiosurgery for non-invasive treatment of cardiac arrhythmia.
- **LUMEN**: This chapter encompasses a wide range of topics related to the LUMEN research group, which focuses on the development of novel medical imaging and therapy techniques. The authors discuss the modeling of drug release from bone implants, the simulation of gentamicin diffusion from a coated intramedullary nail, and the investigation of particle dynamics near the endothelial glycocalyx using multi-focus FCS. They also present a holographic detection system for non-contact photoacoustic tomography, a physical model of perfused pulsating tissue compartments, a method for measuring the oxygen content of cerebral efferent vessels, and a description of a novel scanner construction for a dynamic field-free line for Magnetic Particle Imaging. The chapter concludes with the experimental evaluation and optimization of a UWB localization system for medical applications and a system for in-ear pulse wave measurements.
Schlüsselwörter (Keywords)
: Medical Engineering, Biomedical Optics, Photoacoustic Imaging, Bio�medical Engineering, Medical Devices, Signal Processing, Electromyography, Magnetic Particle Imaging, Imaging and Image Computing, Magnetic Resonance Imaging, Brain Connectivity, Pulmonary Embolism, Bone Implants, Endothelial Glycocalyx, Photodynamic Therapy, Glioma Cells, Photosensitizer Delivery, Sunscreen, Metadynamics, Pyroelectric Detectors, Gas Measurement, Infusion Systems, Flow Regulation, Short-fiber-filled Epoxy, Brachytherapy, Reprocessing, Single-use Devices, Medical Device Directive (MDD), Software Testing, Hand Prostheses, Eye-Blink Visualisation, Machine Vision, Heart Reference Point, Kinect Sensor, Stroke Lesions, GABA Separation, Cardiac Arrhythmia, Radiosurgery, Drug Release, Diffusion Modeling, Endothelial Surface Layer, Fluorescence Correlation Spectroscopy, Microfluidic Chip, Field-Free Line, Magnetic Particle Imaging, Scanner Construction, UWB Localization, In-ear Pulse Wave Measurements, Pulse Arrival Time, Heart Rate Variability.
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- T. M. Buzug et al. (Autor), 2014, Student Conference Medical Engineering Science 2014, Múnich, GRIN Verlag, https://www.grin.com/document/268650
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