The study examined the properties of various plant extracts. Dracaena cinnabari of which that exhibited the highest ethanol extractive value, low moisture content, and contained specific phytochemical classes. Valachia nilotica subsp. indica, Capparis cartilaginea, and Fagonia paulayana displayed variations in their phytochemical profiles. Gas-Chromatography-Mass Spectrometry (GC-MS) and Fourier- Transform Infrared Spectroscoy (FTIR) analysis aided in identifying the bioactive compounds present in these medicinal plants, suggesting their potential for therapeutic applications. The findings provide valuable insights into the properties and potential uses of these plant extracts (Ethanol70% and Aqueous).
Dracenia cinnabari, Capparis cartilaginea, Vachellia nilotica subspecies indica, and Fagonia paulayana are medicinal plants used in traditional Yemen medicine for the treatment a variety of infectious and non-infectious diseases. These plants were selected to evaluate their potential antibacterial, antifungal and Trichomoniasis- anti activity. The plant samples (Aden, Lahaj, and Abyan governorates. Dracaena cinnabari. specimens were collected from different locations on the island of Socotra
during the winter of 2019) used in this study were processed at the biology laboratory of the Faculty of Education in Aden. Microbiological procedures, including the isolation and identification of bacteria, fungi, and Trichomonas vaginalis, were conducted at the laboratories of the Supreme Board of Drugs and Medical Appliances. The research took place from January 2020 to August 2023, focusing on the city of Aden in Yemen. The study encompassed various healthcare facilities, both public and private, including the German Aden Hospital, Al-Sadqah Hospital, Al-Madinah Medical Center, Al-Hanan Medical Center, and Aden German International Hospital. The choice of Aden was based on its environmental conditions, such as high temperatures, humidity, and inadequate hygiene prastic, which contribute to the increased prevalence of bacterial and fungal infections.
Inhaltsverzeichnis (Table of Contents)
- Chapter I. Introduction
- 1.1. The general objective of study
- 1.2. Our study aimed to achieve the following objectives
- 2. Literature Review
- 2.1. Background of the plants:
- 2.1.1. Medicinal Plants of the World
- 2.1.2. Medicinal Plants in Yemen
- 2.2. The studied plants:
- 2.2.1. Family: Dracaenaceae
- 2.2.1.1. Description of the family Dracaenaceae
- 2.2.1.2. Description of the species Dracaena cinnabari
- 2.2.1.3. Scientific Classification Dracaena cinnabari
- 2.2.1.4.Folk Medicine and Heritage Resources of Dracaena cinnabari
- 2.2.2. Family Fabaceae
- 2.2.2.1. Description of the family Fabaceae
- 2.2.2.2 Leguminosae Juss. Subfam. Mimosideae
- 2.2.2.3. Vachellia nilotica Babool (Acacia nilotica)
- 2.2.2.4. Scientific Clasificación Vachellia nilotica
- 2.2.2.5. Description of the Vachellia nilotica subsp. indica (Benth.) Kyal. & Boatwr
- 2.2.2.6. Folk Medicine and Heritage Resources of Vachellia nilotica subsp. indica (Benth.) Kyal. & Boatwr
- 2.2.3. Family Capparisaceae
- 2.2.3.1. Description of the family Capparaceae
- 2.2.3.2. Description of the species Capparis cartilaginea Decne
- 2.2.3.3. Scientific Classification of the species Capparis cartilaginea Decne.
- 2.2.3.4. Folk Medicine and Heritage Resources Capparis cartilaginea Decne.
- 2.2.4. Zygophyllaceous (Creosote- bush, or Caltrops Family)
- 2.2.4.1. Description of family Zygophyllaceous
- 2.2.4.2. Description of Fagonia paulayana Wagner & Vierh. Mga synonym.
- 2.2.4.3. Scientific Classification of Fagonia paulayana
- 2.2.4.4. Folk medicine and heritage resources of Fagonia paulayana
- 2.3. Chemical analysis of plant extract's:
- 2.3.1. Gas Chromatography-Mass Spectrometry (GC-MS)
- 2.3.2. Fourier-transform infrared spectroscopy (FTIR)
- 2.4. Vaginal Microorganisms
- 2.4.1. Microbial vagina background
- 2.4.2. Microbial human vaginal isolates
- 2.4.3. Healthy Vaginal
- 2.4.4. Vaginal microbial Flora (Microbiota)
- 2.4.5. Interaction with the Vaginal Flora
- 2.4.6. Bacterial Vaginosis (BV)
- 2.4.7. Vulvovaginal candidiasis
- 2.4.8. Trichomoniasis
- 2.5. Antimicrobial Resistances of vagina microbial
- Chapter III. Materials and Methods
- 3.1. Material used in our Study
- 3.2. Others materials
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This doctoral thesis investigates the efficacy of various Yemeni plants, including Dracaena cinnabari, against vaginal bacterial, fungal, and parasitic isolates. The main objective is to assess the antimicrobial properties of these plants and contribute to the understanding of their potential use in treating vaginal infections. The research aims to provide scientific evidence supporting or refuting their traditional medicinal applications.
- Antimicrobial properties of Yemeni plants
- Traditional medicinal uses of plants in Yemen
- Vaginal microbiota and infections
- Chemical analysis of plant extracts
- Assessment of antimicrobial resistance
Zusammenfassung der Kapitel (Chapter Summaries)
Chapter I: Introduction: This chapter sets the stage for the research by introducing the general objective of studying the efficacy of Yemeni plants against vaginal infections. It establishes the context by outlining the specific objectives the study intends to achieve. The chapter then transitions into a detailed literature review, examining the background of medicinal plants globally and specifically in Yemen, focusing on the plants selected for the study: Dracaena cinnabari, Vachellia nilotica, Capparis cartilaginea, and Fagonia paulayana. The review also delves into the background of vaginal microorganisms, including those associated with healthy vaginal flora and those responsible for infections such as bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis. The review concludes by examining antimicrobial resistance patterns in vaginal microbes, laying the groundwork for understanding the significance of finding effective alternative treatments.
Chapter II: Literature Review: Building upon the introduction, this extensive chapter provides a detailed exploration of the selected Yemeni plants. Each plant is analyzed, including its botanical classification, description, and traditional medicinal uses. The detailed descriptions encompass the families to which they belong, their scientific classifications, and documented folk uses. This section thoroughly describes the chemical analysis techniques (GC-MS and FTIR) that were employed to analyze the plants' chemical makeup. Following this, the chapter delves into a thorough exploration of vaginal microorganisms, encompassing healthy vaginal flora, pathogenic organisms, and associated infections like bacterial vaginosis, candidiasis, and trichomoniasis. A critical section highlights current knowledge on antimicrobial resistance in vaginal microbes, providing a comprehensive context for the study’s proposed investigation of alternative treatments.
Chapter III: Materials and Methods: This chapter details the materials and methods employed throughout the research. It describes the specific plants used, the collection methods, and the procedures used to extract and analyze the plant compounds. This section also outlines the protocols used for isolating and identifying vaginal bacterial, fungal, and parasitic organisms, and the methods used to assess antimicrobial susceptibility testing. This chapter is crucial as it establishes the reproducibility and validity of the study's results.
Schlüsselwörter (Keywords)
Dracaena cinnabari, Yemeni plants, vaginal infections, antimicrobial activity, bacterial vaginosis, candidiasis, trichomoniasis, GC-MS, FTIR, antimicrobial resistance, traditional medicine, ethnobotany, vaginal microbiota.
Frequently asked questions
What is the main topic of this document?
This document provides a language preview, including a table of contents, objectives, key themes, chapter summaries, and keywords, related to a doctoral thesis investigating the antimicrobial properties of Yemeni plants against vaginal infections.
What is the study's primary objective?
The main objective is to assess the antimicrobial properties of specific Yemeni plants, such as Dracaena cinnabari, against vaginal bacterial, fungal, and parasitic isolates, and evaluate their potential use in treating vaginal infections.
Which Yemeni plants are the focus of the research?
The research primarily focuses on the following plants: Dracaena cinnabari, Vachellia nilotica, Capparis cartilaginea, and Fagonia paulayana.
What vaginal infections are examined in the study?
The study examines bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis.
What are the key themes of the research?
The key themes include antimicrobial properties of Yemeni plants, traditional medicinal uses of plants in Yemen, vaginal microbiota and infections, chemical analysis of plant extracts, and assessment of antimicrobial resistance.
What chemical analysis techniques are used in the study?
Gas Chromatography-Mass Spectrometry (GC-MS) and Fourier-transform infrared spectroscopy (FTIR) are used for chemical analysis of plant extracts.
What does Chapter I cover?
Chapter I introduces the study's objectives, provides a literature review on medicinal plants globally and in Yemen, focuses on the selected plants, and covers the background of vaginal microorganisms, including those associated with healthy vaginal flora and infections.
What does Chapter II cover?
Chapter II is a detailed literature review that expands on the plants and vaginal microorganisms. Each plant is analyzed with botanical description and traditional uses. There is also a thorough exploration of vaginal flora, pathogenic organisms and associated infections.
What does Chapter III cover?
Chapter III details the materials and methods used in the research, including plant collection, extraction procedures, compound analysis, methods for isolating and identifying vaginal organisms, and antimicrobial susceptibility testing.
What are some of the keywords associated with this research?
Keywords include: Dracaena cinnabari, Yemeni plants, vaginal infections, antimicrobial activity, bacterial vaginosis, candidiasis, trichomoniasis, GC-MS, FTIR, antimicrobial resistance, traditional medicine, ethnobotany, vaginal microbiota.
- Citar trabajo
- Dr. Nohad Fartwt (Autor), 2024, Assessing the Efficacy of Dracaena cinnabari and other Yemeni Plants Against Vaginal Bacterial, Fungal, and Parasitic Isolates, Aden-Yemen, Múnich, GRIN Verlag, https://www.grin.com/document/1553532
