Extrait
Contents
Introduction
Definition Gliomas and Glioblastomas
Isocitratdehydrogenase- Gene & the Enzyme IDH
Epidemiology and Prognosis
Cell of origin, Epigenetics & Genetic Pathways of Tumorigenesis
Treatment Implications of IDH
Indications for a Systematic Review
Aims
Methodology
Research Question
Databases
Search strategy
Study Selection
Eligibility criteria
Inclusion criteria
Exclusion criteria
Study Analysis/ Quality Assessment
Results
Search results
Study and participant characteristics
Analysis of Data & Discussion
Conclusion
References
Appendices
Appendix 1- the Search Strategy
Appendix 2- PRISMA flowchart
Appendix 3- Quality Assessment
A) Newcastle-Ottawa Scale
B) CASP-Tool
Appendix 4- Results-Table
Figures
Figure 1 — Diffuse Gliomas: from histology, IDH status and other genetic parameters
Figure 2 - Potential mechanism implicated in tumorigenesis induced by IDH MUTATION
- Citation du texte
- Ronja Handwerker (Auteur), 2018, Review of therapy response and survival of patients with glioma or glioblastoma and IDH mutation, Munich, GRIN Verlag, https://www.grin.com/document/465476
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